AOPs 101: The How and Why of Development and Use
This workshop will compliment several presentations on Adverse Outcome Pathways at the SOT meeting, and is intended for those scientists who are not yet familiar with the AOP concept but would like to learn to apply it to their own work or to become involved in ongoing projects.
Development of a Knowledge Base for Quantitative Modeling of Adverse Outcome Pathways: Stakeholder Input Sessions
All are invited to provide input on the functional requirements of IT tools being developed jointly by the OECD, EC JRC, and US EPA to model AOPs.
Click the image below to enlarge and download PDF:
53rd Annual Meeting and ToxExpo
Society of Toxicology
March 24-27, 2014
Late-breaking abstracts accepted until Jan. 6, 2014.
DNT4: Fourth International Conference on Alternatives for Developmental Neurotoxicity Testing
May 12-14, 2014
Developmental neurotoxicity from chemical exposures is a growing concern. The developing human nervous system is susceptible to pharmaceuticals and environmental contaminants, and exposure during development is known to cause lasting neurological deficits. This conference will bring together diverse stakeholders from around the globe, including research scientists, regulators, industry representatives, academics, and pediatricians.
Abstract Submission Deadline: Dec. 31, 2013
European Society of Toxicology In Vitro 2014 International Conference
June 10-13, 2014
Egmond aan Zee, The Netherlands
The 16th International Workshop on Quantitative Structure-Activity Relationships in Environmental and Health Sciences will take place on June 16-20, 2014 at the IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
March 4th 2014 Oral and poster presentation abstract submission deadline
March 21st 2014 Early registration deadline
April 22nd 2014 Late poster presentation abstract submission deadline
9th World Congress on Alternatives and Animal Use in the Life Sciences
Humane Science in the 21st Century
Aug. 24-28, 2014
Prague, Czech Republic
Abstract Submission Deadline: April 1, 2014
- COSMOS DB: A New Database of Toxicological Information to Support Knowledge Discovery | Mark Cronin, Liverpool John Moores University and COSMOS project coordinator
- High Content Imaging Approaches in Neurotoxicology and Neurodegeneration Research | Marcel Leist, University of Konstanz and CAAT Europe
- EURL ECVAM's Approach to Validation of Alternative Methods | Valerie Zhuang, EURL ECVAM
- Using the AOP Framework to Develop HTS Assays for Thyroid-Disrupting Chemicals | Katie Paul, US EPA
- The Role of Non-Animal Methods in the Regulation of Nanomaterials in the United States | Erik Janus, Steptoe and Johnson LLP (Recording not available)
- Human Induced Pluripotent Stem Cell-derived Model Systems | Maureen Bunger, Cellular Dynamics
- Incorporating New Technologies into Toxicity Testing and Risk Assessment | Russell Thomas, The Hamner Institutes for Health Science
- The Virtual Embryo | Nicole Kleinstreuer, US EPA
- Tox21 Program Update | Raymond Tice, National Toxicology Program, NIH
- Evidence-Based Toxicology (EBT) for the 21st Century | Martin Stephens, Johns Hopkins University
- Effectopedia: The Online Encyclopedia of Adverse Effect Pathways | Gilman Veith and Hristo Aladjov, International QSAR Foundation
- MetaPath: A Metabolism Pathway Database | Patricia Schmeider, US EPA
Second Annual Scientific Meeting of the American Society for Cellular and Computational Toxicology: The Future Is Here: Practical Applications of Emerging Scientific Tools
Human Organs on Chips as Replacements for Animal Testing, the keynote address given by Donald E. Ingber, M.D., Ph.D., of the Wyss Institute at Harvard, kicked off the meeting which featured a dozen lectures and poster presentations on making toxicology a more human-relevant science. Other topics included methods to replace live animals in eye irritation tests and computer-based virtual embryos that show how chemical exposures might affect developing embryos. ASCCT members, click here to view select presentations.
First Annual Scientific and Business Meeting of the ASCCT
The first annual ASCCT meeting focused on advances in the fields of in vitro and computational toxicology. Dr. Melvin Andersen, associate director of The Institute for Chemical Safety Sciences at The Hamner Institutes for Health Sciences and ASCCT board member, gave a plenary lecture on Computational Cellular Pathway Modeling: Combining Key In Vitro and In Silico Tools to Enhance Modern Safety Assessment. Dr. Suzanne Fitzpatrick, senior advisor for toxicology at the U.S. Food and Drug Administration gave a plenary lecture on an Overview of the FDA-DARPA-NIH Collaboration on Human/Organ on a Chip.
Institute for In Vitro Sciences Practical Methods for In Vitro Toxicology Workshop
Attendees gained hands-on laboratory experience and instruction in the practical application of the lectured topics. Topics for the three and a half day course included: (i) international regulatory acceptance status of in vitro assays, (ii) predicting organ specific toxicity (e.g., ocular, dermal and hepatic), (iii) using cell and organ culture models with histological, biochemical, and molecular endpointsm, and (iv) data interpretation.
2010 In Vitro Alternatives Forum
Thank you for contributing to a successful forum. Read the post-meeting report.
8th World Congress for Alternatives and Animal Use
Thank you for helping to make the ASCCT/ESTIV luncheon session a success. A manuscript outlining the discussions that took place during the session has been published. You can view the entire proceedings here.